Ambretone – Technical & Sensory

Ambretone

Ambretone – Technical & Sensory Overview

Executive Summary

Ambretone is a specialty musk–amber aroma compound with rich, long-lasting warmth and a subtly sweet, floral nuance. Designed for fine fragrances, personal care, and household formulations, it provides exceptional depth, smooth diffusion, and fixation power. In perfumery, Ambretone brings body, volume, and sensuality to musk, amber, floral, and animalic accords.

What Is Ambretone? (Chemistry & Structure)

• Chemical Name: 5-Cyclohexadecen-1-one

• Synonym: 5-Cyclohexadecenone

• Molecular Formula: C₁₆H₂₈O

• Molecular Weight: 236.99 g/mol

• Chemical Class: Macrocyclic ketone (musk/amberone type)

• Natural Status: Synthetic – not found in nature

Key Identifiers & Compliance Snapshot

Parameter	Specification / Value
CAS Number	37609-25-9
Purity (GC)	≥ 98 % (main peak)
Flash Point	170 °C
Vapor Pressure (25 °C)	≈ 0.03 Pa
CLogP	5.82
Appearance	Colorless, clear liquid
Typical Use Level	< 10 % in formulations
Occurrence in Nature	Not found in nature
Recommended Grade	Perfume & Functional (P&F)

Sensory Profile & Performance

• Olfactory Signature: Musky, sweet, floral, amber, softly animalic

• Diffusion: Moderate to strong – perceptible at low concentrations

• Tenacity (on blotter): > 7 days

• Substantivity:

  • Skin: Good

  • Dry Fabric: Good

  • Wet Fabric: Good

  • Hair: Good

Stability & pH Dependence

• Stable in acidic to neutral conditions (pH 3 – 10)

• Reduced stability in strong alkaline environments (pH ≈ 14)

• Recommendation: Store in tightly sealed, light-protected containers; include antioxidants to minimize oxidation.

Ambretone

Applications & Typical Uses

Fragrance Applications

• Fine perfumes, eaux de parfum, and luxury musky bases

• Amber and animalic accords

• Floral or woody blends requiring warmth and fixation

Personal & Home Care Applications

• Shampoos, body lotions, deodorants

• Fabric softeners and laundry detergents

• Air care and candles

Formulation Strategy & Pairings

Role: Adds depth, longevity, warmth, and a smooth musky undertone.

Pairs Well With:Lactones, amber notes, sandalwood, Iso E Super, Cashmeran, floral bases, and soft balsamic materials.

Formulation Tips:

• Add antioxidants to maintain freshness.

• Combine with long-lasting woody or balsamic bases.

• Avoid high-pH formulations.

Regulatory & Safety Overview

• IFRA Restrictions: None at typical usage levels

• Toxicity: Low; may cause mild irritation at high concentrations

• Allergen Status: Not listed among EU 26 fragrance allergens

• GRAS / FEMA: Not applicable (fragrance use only)

Analytical & Quality Control

• Identification: GC-MS retention index and mass spectrum

• Assay: ≥ 98 % GC area purity (Galbora P&F Standard)

• Monitoring: Evaluate oxidation and pH-dependent degradation

Purchasing Checklist

☑ Confirm P&F grade and ≥ 98 % purity (COA)

☑ Verify SDS, IFRA, and allergen documentation

☑ Check storage and stability data

☑ Run pilot tests in target fragrance bases

This article was researched and written by Galbora.

Use of this content is permitted when citing the source.

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