Ambretone – Technical & Sensory
Updated: Oct 17
Ambretone – Technical & Sensory Overview
Executive Summary
Ambretone is a specialty musk–amber aroma compound with rich, long-lasting warmth and a subtly sweet, floral nuance. Designed for fine fragrances, personal care, and household formulations, it provides exceptional depth, smooth diffusion, and fixation power. In perfumery, Ambretone brings body, volume, and sensuality to musk, amber, floral, and animalic accords.
What Is Ambretone? (Chemistry & Structure)
Chemical Name: 5-Cyclohexadecen-1-one
Synonym: 5-Cyclohexadecenone
Molecular Formula: C₁₆H₂₈O
Molar mass (calculated from formula): approx. 236.39 g/mol
Chemical Class: Macrocyclic ketone (musk/amberone type)
Natural Status: Synthetic – not found in nature
Key Identifiers & Compliance Snapshot
Parameter | Specification / Value |
CAS Number | 37609-25-9 |
Purity (GC) | ≥ 98 % (main peak) |
Flash Point | 170 °C |
Vapor Pressure (25 °C) | ≈ 0.03 Pa |
CLogP | 5.82 |
Appearance | Colorless, clear liquid |
Typical Use Level | < 10 % in formulations |
Occurrence in Nature | Not found in nature |
Recommended Grade | Perfume & Functional (P&F) |
Sensory Profile & Performance
Olfactory Signature: Musky, sweet, floral, amber, softly animalic
Diffusion: Moderate to strong – perceptible at low concentrations
Tenacity (on blotter): > 7 days
Substantivity:
Skin: Good
Dry Fabric: Good
Wet Fabric: Good
Hair: Good
Stability & pH Dependence
Stable in acidic to neutral conditions (pH 3 – 10)
Reduced stability in strong alkaline environments (pH ≈ 14)
Recommendation: Store in tightly sealed, light-protected containers; include antioxidants to minimize oxidation.
Applications & Typical Uses
Fragrance Applications
Fine perfumes, eaux de parfum, and luxury musky bases
Amber and animalic accords
Floral or woody blends requiring warmth and fixation
Personal & Home Care Applications
Shampoos, body lotions, deodorants
Fabric softeners and laundry detergents
Air care and candles
Formulation Strategy & Pairings
Role: Adds depth, longevity, warmth, and a smooth musky undertone.
Pairs Well With:Lactones, amber notes, sandalwood, Iso E Super, Cashmeran, floral bases, and soft balsamic materials.
Formulation Tips:
Add antioxidants to maintain freshness.
Combine with long-lasting woody or balsamic bases.
Avoid high-pH formulations.
Regulatory & Safety Overview
Fragrance use: Check the current IFRA Standards and supplier restriction information for the exact material and intended finished-product category.
Safety: Use the current SDS for the supplied grade to determine hazard classification, handling precautions and exposure controls.
Allergen status: Request a current supplier allergen declaration and assess finished-product labelling under applicable requirements, including EU Regulation 2023/1545 for cosmetics.
GRAS / FEMA: Not applicable (fragrance use only)
Analytical & Quality Control
Identification: GC-MS retention index and mass spectrum
Assay: ≥ 98 % GC area purity (Galbora P&F Standard)
Monitoring: Evaluate oxidation and pH-dependent degradation
Purchasing Checklist
☑ Confirm P&F grade and ≥ 98 % purity (COA)
☑ Obtain the current SDS, applicable IFRA restriction information and supplier allergen declaration
☑ Check storage and stability data
☑ Run pilot tests in target fragrance bases
This article was researched and written by Galbora.
Use of this content is permitted when citing the source.
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